Our Coagulation Medical Practice wants you to live a healthier life!
Our Coagulation Medical Practice wants you to live a healthier life!
Call (949) 581-0555
LDL Apheresis removes low density lipoproteins (LDL) that transport cholesterol in the plasma portion of the blood. The Liposorber filter removes the LDL cholesterol from the plasma. The blood and plasma is then returned to the patient by the IV access. One procedure can lower LDL cholesterol by 70% to 83%.
Great Advances have occurred in the treatment of elevated blood cholesterol leading to a significant reduction in the number of deaths due to heart attacks and stroke.
There remains a group of patients with treatment resistant elevated blood cholesterol that continues to lead to strokes and heart attacks. These Patients lives are improved by a medical instrument that removes the bad cholesterol. It is called Column Absorption Apheresis.
If a person continues to demonstrate elevated Lipoprotein(a) or LDL cholesterol despite routine medication or if medication treatment has lead to significant muscle pain. Column Absorption Apheresis will improve the quality of life and be life saving.
Familial Hypercholesterolemia (FH) is an inherited disorder that causes very high cholesterol levels and greatly increases the chance of having a heart attack early in life. Heart attacks usually occur in men when they are 40-55 years old and in women when they are 50-65 years old. Unfortunately, they can sometimes occur when people are in their mid-twenties. The first case of FH was described over 100 years ago and characteristics of FH passing from generation to generation was understood in the late 1930's. Actual genetic proof was discovered in the 1960's and 1970's.
Cholesterol is removed from the blood by the liver using Low Density Lipoprotein (LDL) receptors. Each person has two genes that are responsible for making the LDL receptors: one received from the father and one received from the mother. In a person with FH, an abnormal gene was passed on from one parent. Therefore, half of the LDL receptors are absent or do not work properly and the other half are normal. Because half of the receptors do not remove the cholesterol normally, cholesterol levels increase in the blood. This results in damage to blood vessels, blockage of arteries and heart attacks at an early age.
If a person has normal cholesterol levels at birth, he or she will never develop FH later in life nor will he or she pass the gene on to their children. If a person has FH, then each of his or her children will have a 50% chance of inheriting FH. You are either born with FH or not. Cholesterol levels can be checked at birth. Most persons with the disease are neither recognized nor treated.
Recent advances in affinity column technology now enable the efficient removal of LDL-cholesterol directly from the bloodstream by apheresis. This new therapeutic tool may reduce the risk of progressive atherosclerotic disease in hypercholesterolemic patients who are resistant to diet and drugs.
The Liposorber System is an extracorporeal treatment, similar to dialysis that removes LDL-cholesterol from the blood. The system consist of three disposable parts which are used and then thrown away after each treatment, with an automated, computerized machine controlling and checking the entire process.
The Liposorber LDL-Adsorption Column selectively binds ApoB-containing lipoproteins (LDL, Lp(a) and VLDL). There is minimal effect on HDL or other plasma proteins.
Transfusion Medicine Associates
24407 Calle De Louisa Suite 100 Laguna Hills, CA 92653 US
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